The H5N1 avian influenza virus has been confirmed in mainland Australia, with detections recorded in Western Australia and South Australia.

H5N1 鳥類流感病毒已在澳洲內地被證實，西澳洲與南澳洲均有紀錄發現。

The epidemiological situation commenced with the confirmation of two infected seabirds near Esperance, Western Australia, subsequently followed by a third confirmed case involving a giant petrel on the Fleurieu Peninsula in South Australia. A further suspected positive case has been identified in the Quindalup area, pending confirmation by the CSIRO’s Centre for Disease Preparedness. While the Western Australian administration reports no evidence of large-scale mortality or transmission to native wildlife, the presence of the virus has necessitated the activation of coordinated government response protocols.

此次疫情始於西澳洲 Esperance 附近證實兩隻海鳥感染，隨後在南澳洲 Fleurieu 半島發現第三宗個案，涉及一隻巨彼得信鵜。在 Quindalup 地區另有一個疑似陽性個案，正等待 CSIRO 疾病準備中心證實。雖然西澳洲政府報告無證據顯示有大規模死亡或傳染至原生野生動物，但病毒的出現已導致必須啟動協調政府應對方案。

Of particular concern to the scientific community is the potential for interspecies transmission to endangered mammals. Wildlife Health Australia and associated researchers have identified marine mammals, specifically seals and sea lions, as high-risk cohorts, citing previous global mortality events. Furthermore, the susceptibility of scavenging marsupials, such as the Tasmanian devil and various quoll species, is a primary focus. It is hypothesized that the Tasmanian devil's diminished genetic diversity and the immune depletion resulting from devil facial tumour disease may exacerbate vulnerability to the virus. Consequently, the federal government has allocated significant funding via the Funding Preparedness initiative to implement protective measures for approximately ten vulnerable marsupial species.

科學界特別關注的是跨物種傳染至瀕危哺乳動物的可能性。Wildlife Health Australia 及相關研究人員將海洋哺乳動物（特別是海豹與海獅）列為高風險群體，理由是先前全球曾發生死亡事件。此外，食腐類有袋類動物（如塔斯馬尼亞惡魔及多種袋鼬）的感病程度亦為主要焦點。據假設，塔斯馬尼亞惡魔基因多樣性的降低，以及面部腫瘤病導致的免疫力損耗，可能會加劇其對病毒的脆弱性。因此，聯邦政府透過「準備金計畫」撥款，為約十種脆弱的有袋類動物實施保護措施。

Institutional responses include the establishment of biosecurity enclosures at the Mulligans Flat sanctuary for eastern quolls and the implementation of roofed enclosures and artificial diets for numbats at Perth Zoo to prevent contamination via avian excreta. Additionally, research into the delivery of oral vaccines via automated bait dispensers is being explored as a long-term contingency. In South Australia, wildlife facilities have implemented lockdown procedures and staff have been administered antivirals as a precautionary measure following the detection of the virus in a rescued giant petrel.

機構回應包括在 Mulligans Flat 保護區為東方袋鼬建立生物安全圍欄，以及在珀斯動物園為袋食蟻獸實施有頂圍欄與人工飲食，以防止經由鳥類排泄物污染。此外，研究人員正探索利用自動誘餌分發器接種口服疫苗，作為長期應對方案。在南澳洲，野生動物設施已實施封鎖程序，且在發現一隻獲救巨彼得信鵜染菌後，工作人員已作為預防措施而服用抗病毒藥物。

Australia has transitioned from a state of preparedness to active management of H5N1, with ongoing surveillance and targeted biosecurity interventions currently in effect.

澳洲已從準備狀態轉入 H5N1 的積極管理階段，目前持續進行監控與針對性的生物安全干預。