Researchers have engineered a cost-effective oral spray derived from sugarcane molasses to reduce malodorous compounds and pathogenic bacteria in dogs.

研究人員研發出一款利用甘蔗糖蜜製成的低成本口腔噴霧，旨在減少犬類口中的異味化合物與病原菌。

The clinical impetus for this development stems from the correlation between canine halitosis—characterized by metallic or putrid odors—and underlying dental pathologies, such as periodontal disease. Conventional therapeutic interventions typically necessitate the administration of antibiotics, chemical rinses, or the mechanical application of enzymatic toothpastes. To provide a sustainable alternative, investigators utilized polyphenols extracted from sugarcane molasses, a byproduct of agricultural refining, which had previously demonstrated antibacterial efficacy in vitro.

此次開發的臨床動機源於犬類口臭（其特徵為金屬味或腐爛味）與潛在牙科病理（如牙周病）之間的相關性。傳統的治療干預通常需要使用抗生素、化學漱口水或機械化地塗抹酵素牙膏。為了提供一個可持續的替代方案，研究人員使用了從農業精煉副產品甘蔗糖蜜中提取的多酚，該物質先前已在體外實驗中證明具有抗菌功效。

In a controlled study involving ten healthy canine subjects exhibiting halitosis, the efficacy of the spray was evaluated via gas chromatography-mass spectrometry (GC-MS) and sensory analysis. The data indicated a substantial reduction in volatile organic compounds, specifically esters, amines, and aldehydes. The researchers asserted that the observed deodorization resulted from the biochemical neutralization of compounds rather than mere olfactory masking. Furthermore, a thirty-day longitudinal application resulted in a significant diminution of pathogenic bacterial populations, notably Porphyromonas and Fusobacterium.

在一項涉及十隻患有口臭且健康的犬類受試者的對照研究中，研究人員透過氣相層析-質譜儀 (GC-MS) 和感官分析評估了該噴霧的功效。數據顯示，揮發性有機化合物（特別是酯類、胺類和醛類）顯著減少。研究人員斷言，所觀察到的除臭效果源於化合物的生化中和，而非單純的嗅覺掩蓋。此外，經過三十天的縱向應用，病原菌群（尤其是 Porphyromonas 和 Fusobacterium）顯著減少。

The mechanism of action is conceptualized as a tripartite process: the polyphenols function as a 'molecular sponge' for the sequestration of odor molecules, a 'switch' for the inhibition of bacterial enzymes, and a 'gardener' for the systematic reduction of harmful microbial colonies.

其作用機制被概念化為一個三部分過程：多酚充當捕捉氣味分子的「分子海綿」，充當抑制細菌酶的「開關」，以及充當系統性減少有害微生物菌落的「園丁」。

The molasses-derived spray demonstrated efficacy in reducing canine oral bacteria and odors, with further trials planned to expand the sample size.

這種糖蜜衍生噴霧證明能有效減少犬類口腔細菌與異味，計畫將進行進一步試驗以擴大樣本數。