A fifteen-year-old resident of Oklahoma has been declared brain dead following the ingestion of excessive quantities of diphenhydramine as part of a viral internet challenge.

一名居住在奧克拉荷馬州的十五歲青少年，因參與一項網路流行挑戰而服用過量苯海拉明，已被宣布腦死亡。

The incident involves Leah Presson, who was admitted to a medical facility in Enid, Oklahoma, after presenting with seizures. While initial diagnostic hypotheses considered the patient's history of asthma, subsequent evidence indicated the ingestion of Benadryl in quantities exceeding therapeutic limits. This behavior is associated with a social media phenomenon termed the 'Benadryl challenge,' wherein participants consume high doses of antihistamines to induce a state of euphoria or altered consciousness. According to the patient's father, Richard Presson, the adolescent had engaged in this specific activity on multiple prior occasions.

該事件涉及 Leah Presson，她在出現癲癇發作後被送入奧克拉荷馬州 Enid 的醫療機構。雖然最初的診斷假設考慮到患者有氣喘病史，但隨後的證據表明她服用了超過治療限制數量的 Benadryl。這種行為與一種被稱為「Benadryl challenge」的社交媒體現象有關，參與者透過服用高劑量的抗組織胺來誘導快感或改變意識狀態。根據患者的父親 Richard Presson 稱，該青少年此前已多次參與此特定活動。

From a clinical perspective, Dr. Ryan Brown noted that while diphenhydramine remains a viable treatment for allergic reactions when administered according to prescribed dosages, supra-therapeutic intake may precipitate cardiac arrhythmias and seizures. Such physiological disruptions can culminate in cardiac arrest, resulting in cerebral hypoxia and the subsequent cessation of all brain activity. Consequently, the patient remained in intensive care for several days before diagnostic tests confirmed the absence of neurological function.

從臨床角度來看，Ryan Brown 醫生指出，苯海拉明在按照處方劑量服用時，仍是治療過敏反應的有效方法，但超治療劑量的攝取可能會導致心律不整和癲癇發作。此類生理功能紊亂可能導致心臟驟停，從而引起腦缺氧，隨後導致所有腦活動停止。因此，患者在加護病房留院數日，直到診斷測試確認神經功能喪失。

In response to the prognosis, the Presson family has initiated the process of organ procurement. Mr. Presson stated that this decision aligns with the patient's altruistic nature, noting that the donation could potentially benefit numerous recipients. He further advocated for increased parental vigilance and the implementation of educational measures to mitigate the proliferation of such hazardous digital trends.

針對此診斷結果，Presson 家族已啟動器官捐贈程序。Presson 先生表示，此決定符合患者無私的天性，並指出捐贈有可能使許多受贈者獲益。他進一步主張應增加家長的警覺性，並實施教育措施，以減緩此類危險數位趨勢的擴散。

The patient has been pronounced brain dead, and her family is proceeding with organ donation.

患者已被宣布腦死亡，其家屬正進行器官捐贈程序。